Premier League actions returns to your TV screens this weekend with quite some interesting fixtures to watch out for. The Manchester Derby looks like the big clash of the weekend although there are other thrilling matchups. Chelsea play host to Brentford as Liam Rosenior hopes to get his first Premier League win as Chelsea manager. Villa and Everton will do battle and Forest is the latest test in Arsenal’s title quest. We have curated the fixtures and made our predictions ahead of busy weekend in Europe’s top leagues. This one is for the Premier League. 
Premier League Predictions Week 22
1) Manchester United vs Manchester City
Prediction: Man City win, 2–1
This is the marquee fixture of the weekend. City arrive in excellent form—unbeaten in recent matches with high scoring output—while United have struggled with consistency and managerial change. United’s defence has leaked goals, but playing at Old Trafford always boosts their resilience. With City announcing the signing of Marc Guehi and Antoine Semenyo having got off to a brilliant start in Sky Blue, expect an exciting game resolved late by City’s superior quality in attack.
2) Chelsea vs Brentford
Prediction: Chelsea win, 2–0
Chelsea have had mixed form but possess clear offensive quality at home. Brentford are competitive but less consistent on the road; a Chelsea win seems likely on the cards with clean‑sheet potential.
3) Leeds United vs Fulham
Prediction: Leeds 1–1 Fulham
Both teams have shown flashes of attacking promise recently but are vulnerable at the back. Fulham still have key players away on AFCON duties. Expect an entertaining draw with goals at both ends.
4) Liverpool vs Burnley
Prediction: Liverpool win, 3–0
Liverpool are still among the top clubs and should comfortably beat relegation‑threatened Burnley. Burnley’s recent form has been poor, and Liverpool will ruthlessly exploit their defensive frailties.
5) Sunderland vs Crystal Palace
Prediction: Sunderland draw, 2–2
Sunderland are tough to beat at home, and Palace can be dangerous on the counter. Expect a tight affair with goals from both sides.
6) Tottenham vs West Ham United
Prediction: Tottenham win, 3–1
Tottenham have the edge over struggling West Ham, who are in relegation trouble. Spurs should score first, though West Ham could hit back late.
7) Nottingham Forest vs Arsenal
Prediction: Arsenal win, 2–0
Arsenal lead the league and are among the season’s most consistent sides. Forest are in relegation‑scrap mode and likely to struggle against Arsenal’s fluid attack.
8) Wolves vs Newcastle United
Prediction: Newcastle win, 2–1
Newcastle are in much better form than bottom‑placed Wolves, whose confidence is low. Expect Newcastle to edge this tight contest on the road. Do not write off Wolves though as they’re well capable of springing up surprises. I reckon they’d get a goal.
9) Aston Villa vs Everton
Prediction: Aston Villa win, 2–1
Unai Emery’s Villa have been seriously strong this season and should see off an Everton side struggling for goals consistency. Expect a competitive match, but Villa will have enough quality to prevail over the visitors at Villa Park.
10) Brighton & Hove Albion vs Bournemouth
Prediction: Brighton win, 2–1
Brighton possess a tactical edge, and Bournemouth continue to be inconsistent. I predict a home win by a slender margin.
Fun stat: Bournemouth have scored in each of their last 7 games in all competitions, scoring 2 or more goals in 5 of those fixtures, including 4 against Man United, 2 against Spurs and 2 against Arsenal. Backing them to continue their scoring streak.
What These Results Mean
Title Race
- A City win keeps them close to Arsenal at the top, maintaining pressure in the title fight.
- Arsenal’s expected win at Forest could see them extend their lead at the summit.
European Spots
- Chelsea, Liverpool, and Newcastle pushing for top‑four status need positive results to keep pace.
- Spurs and Fulham’s draws/wins keep them in the conversation, but they can’t afford many slip‑ups.
Relegation Battle
- Burnley and Wolves look destined to stay in the drop zone unless something dramatic changes.
- Sunderland and Palace remain in the middle, and every point tests their Premier League survival credentials.
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